Bioengineering Heat Transfer by Young I. Cho (Eds.)

By Young I. Cho (Eds.)

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Influence of pulsatile blood flow and heating scheme on the temperature distribution during hyperthermia treatment. Int J Heat Mass Tran 2007;50:4883–90. [27] Song CW, Lokshina A, Rhee JG, Paten M, Levitt SH. Implication of blood flow in hyperthermia treatments of tumors. IEEE Trans Biomed Eng 1984;31:9–16. [28] Craciunescu OI, Clegg ST. Pulsatile blood flow effects on temperature distribution and heat transfer in rigid vessels. J Biomech Eng 2001;123:500–5. 5 HYPERTHERMIA TREATMENT PLANNING 41 [29] Horng TL, Lin WL, Liauh CT, Shih TC.

This complexity is related to mass flow rates, inlet temperatures, and directions of vessels. Therefore, prior to hyperthermia treatments, thermally significant blood vessels should be identified and handled carefully in order to reduce their cooling effects on the treated region, particularly to those vessels flowing into the treated region. 5 kg/m3/s with no vasculature present and after optimization with fine spatial power deposition. The ideal temperature is set to be 43  C. (a-e) are the temperature distributions at x ¼ 38 mm (4 mm away from the front boundary), x ¼ 42 mm (the front boundary), x ¼ 52 mm (middle of the treated region), x ¼ 62 mm (the back boundary), and x ¼ 66 mm (4 mm away from the back boundary) planes, respectively, after optimization.

Thus, attempting to model complicated vascular geometry in which blood circulates along those different sizes of vessels is an important approach to analyze precisely the heat transfer processing in a biothermal system. To account for the impact of large blood vessels on the heat transfer processes, thermal models have to take conductive and convective heat transport into account. And many researchers have attempted to describe the impacts of the blood vessels [18]. Some of the vascular models have been designed not for application in hyperthermia treatment planning, but to obtain basic insight into the heat transfer between large blood vessels and tissue.

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