By Jacky Law
Final 12 months the pharmaceutical had revenues in way over $300 billion. basically a technique or one other all of us pay — no matter if we purchase the medicine without delay or via taxation. yet is it much less transparent that we're getting worth for funds? in a single of the 1st self sufficient investigations of the trendy healthcare procedure, Jacky legislations exhibits how a small variety of enterprises have come to dominate the healthcare time table in Britain and the USA. She finds a approach during which the relentless pursuit of revenue is crowding out the general public reliable. potent regulators are lower than extreme strain from company lobbies, and corporations spend extra money on advertising than they spend on study and improvement. in the meantime the price of new medicinal drugs rises relentlessly whereas the variety of unique new items declines. All isn't good with smooth medication. In what's either a prognosis and a process remedy, the writer finds an international the place marketplace concerns, now not clinical want, are deciding upon the learn schedule. She issues to a destiny the place the general public and the clinical career once more have a voice within the type of healthcare we need — and the healthcare we pay for.
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Extra resources for Big Pharma: Exposing the Global Healthcare Agenda
1-19 to 21 Conventional and subgross histological images of ducts from the regions outlined in the rectangles on the mammogram below. Ex. 1-20 Ex. 1-21 Ex. 1-22 The casting type calcifications are of higher and uniform density; smoothcontoured in the central portion of the lesion (rectangles). Few viable cancer cells accompany them. Ex. 1-22 Fragmented Casting Type Calcifications 21 Characteristic Mammographic and Histological Presentation of Fragmented Casting Type Calcifications on the Mammogram The largest number of viable cancer cells is usually found at the periphery of the region with calcifications.
1-9 Ex. 1-6 to 9 Typical histological appearance of these mammographically detected fragmented casting type calcifications showing large, polymorphic nuclei with frequent mitoses, solid cell proliferation, extensive intraluminal necrosis, and amorphous calcifications. 1 continued Ex. 1-10 Ex. 1-11 Ex. 1-12 Ex. 1-10 to 12 Histological examination of cases with extensive fragmented casting type calcifications often reveals ducts where the necrosis encompasses the entire duct lumen, with few or no viable cancer cells remaining.
7-10 Dotted Casting Type Calcifications 49 Mammographic−Histological Correlation of Dotted Casting Type Calcifications on the Mammogram Ex. 7-11 Ex. 7-12 Ex. 7-11 & 12 The extreme distension of the cancerous ducts is mainly caused by the necrotic, extensively calcified debris. The micropapillary cell proliferation can be followed along the basement membrane, while the von Kossa (silver nitrate) staining depicts the calcifications in black. Ex. 7-13 Higher-magnification histological image demonstrates the disproportionately small volume of the papillary cell growth in relationship to the massive volume of necrotic debris.